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Article: Benefits and harms of prescription drugs and supplements for treatment of clinical Alzheimer-type dementia: a systematic review and meta-analysis
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Description
The article was co-authored by Northwestern Health Sciences University researcher Mary L. Forte. The article was published in Annals of Internal Medicine and was published in 2020.
Abstract
Purpose: To summarize evidence on the effects of prescription drugs and supplements for CATD treatment.
Conclusion: Cholinesterase inhibitors and memantine slightly reduced short-term cognitive decline, and cholinesterase inhibitors slightly reduced reported functional decline, but differences versus placebo were of uncertain clinical importance. Evidence was mostly insufficient on drug treatment of BPSD and on supplements for all outcomes.